Ten normal adult human subjects received a rapid intravenous infusion of two liters of cold (4ºC) isotonic saline on two separate test days, and we measured their core body temperature, shivering, hemodynamics and sedation for two hours. On one test day, fluid infusion was preceded by placebo infusion. On the other test day, fluid infusion was preceded by 1.0 µg/kg bolus of dexmedetomidine over 10...
Accumulating evidence suggests that physical activity improves explicit memory and executive cognitive functioning at the extreme ends of the lifespan (i.e., in older adults and children). However, it is unknown whether these associations hold for younger adults who are considered to be in their cognitive prime, or for implicit cognitive functions that do not depend on motor sequencing. Here we report...
With an emphasis on reaching historically underrepresented populations, the datasets from the All of Us Research Program include: Electronic health records (OMOP CDM used to standardize all EHR data) Biosamples (blood, urine, and saliva) Mobile health data (from wearable devices that may track biometric data like heart rate and blood pressure) Physical measurements (height, weight, BMI,...
This dataset represents "the minimal underlying data that an independent researcher would need in order to replicate the results” from the associated study which assessed the independent effect of HIV on subjective and objective measures of cardiac and pulmonary function. Adult (18 years or older) persons living with HIV (PLWH) and HIV-uninfected individuals were recruited from the University...
Clinodactyly can be broadly defined as curvature of the finger(s) occurring distal to the metacarpophalangeal joint(s). The most common form of clinodactyly involves a radial curvature of the fifth finger. This dataset provides measured fifth finger curvature (left and right) in a sample of 1,295 U.S. adults recruited from the Western Pennsylvania region as part of two large epidemiological studies...